This section of Hematology and Oncology focuses on the embryological and developmental aspects of blood formation, with special emphasis on fetal erythropoiesis and hemoglobin development. It explains how red blood cell production changes during different stages of fetal life and how hemoglobin adapts to meet the oxygen needs of the developing fetus.
Fetal erythropoiesis occurs in distinct sites throughout development:
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Yolk sac: from 3 to 8 weeks of gestation
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Liver: from 6 weeks until birth
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Spleen: from 10 to 28 weeks
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Bone marrow: from 18 weeks through adulthood
Understanding these stages is essential for recognizing normal hematologic development as well as congenital and acquired blood disorders. This content is designed to support medical and health science students in building a strong foundation in hematology and oncology.
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